Lin Gao Qiming

Chapter 336 The Dilemma of the Pharmaceutical Factory

Just think about the subtropical climate, jungle, and water network terrain. Shi Youren believes that more than half of the world's pathogens can be found in this ghost place.My mentor in the United States will definitely have a soft spot for this place.It's a pity that he wasn't tricked at the time.This old rice is as strong as a cow, but it is a good labor force for the Ministry of Health.At least let him test the poo.

Looking at the pile of poop sample jars in front of him, the grief and indignation in Shi Yanren's heart was unimaginable to others - he was sent here to deal with poop naturally, a big hole called a beast.

To make matters worse, Shi Yiren noticed that the infection rate was starting to rise.He detected more than ten kinds of parasitic eggs such as Clonorchis sinensis and Taenia solium from asymptomatic people.There may be more bacterial carriers, but because the complexity of bacterial testing is much greater, many of them cannot be diagnosed.In a word, no one realizes the complexity of modern medical testing.

The ignorance and indifference of ordinary people who traveled through various parasites and infectious diseases made him even more troublesome.Those who eat wild fruits, those who hunt in private, and those who mess with local women...

When reporting to the executive committee, there is always a hmm, no specific countermeasures, and no attention at all!

Maybe the occurrence of an infectious disease pandemic will clear the heads of Mr. Wen and Mr. Ma?Shi Yanren put the petri dish under the microscope and looked at it carefully.

Fortunately, neither the Vibrio bacterium of cholera nor other bacteria that cause severe infectious diseases appeared in the sample.On the contrary, a large number of Salmonella bacteria were detected. It seems that this unlucky guy is suffering from acute enteritis.Theoretically speaking, for general acute enteritis, as long as the patient is not dehydrated and has no electrolyte disturbance, he can recover with simple antidiarrheal drugs.

"If there are some antidiarrheal medicines in the quarantine camp and some salt water, this person will not die." Shi Yanren felt a little regretful, as long as there were belladonna tablets and a few bottles of normal saline, he would be able to recover.

Considering that the weather is getting hotter and the gastrointestinal diseases are frequent, I have to look for cheap and easy-to-obtain antidiarrheal medicines immediately.Suddenly he thought of the opium in the warehouse of the Ministry of Health.After buying it from Macau, it has been thrown in the warehouse.Although opium is a drug, it has a strong effect on pain relief, cough relief and diarrhea.It is a panacea that is urgently needed now.

Shi Yanren disposed of the specimens, washed his hands again, lit a cigarette, and called Wu De, telling him that the yellow disease alert in the quarantine camp could be lifted.Then he called Wu Nanhai again, asking him to pay attention to the sanitation of the canteen and food processing factory.

"...tomorrow," Shi Yanren looked at the schedule, "I'll come to make an inspection in person, and I'll help you with some summer hygiene precautions."

"Okay, welcome." Wu Nanhai's voice sounded a little nervous on the phone.

"Don't be nervous, I'm not the health bureau coming down to fine you." Shi Yanren said, "Don't do a surprise cleaning, let me see the real situation, so that I can prescribe the right medicine. You come to a donkey dung powder, but see If there is no problem, something big will happen in the future.”

After taking care of Wu Nanhai's health checks, Shi Yanren wanted to make another phone call to the drug factory, but then he thought it would be better to go there by himself, and take a break along the way - he has been smelling poop since 5 o'clock in the morning, and it's almost noon up.If you go to the pharmaceutical factory, you can also go to the farm for a meal.

The medical equipment factory is located inside the farm, and it is a composite reinforced concrete frame building.A chimney was spewing smoke into the air.It is equipped with a dedicated boiler room, ground energy air conditioner, self-provided purified water source and a dedicated garbage incinerator.The overall infrastructure is first class.However, it was Shi Yanren's first visit here after the pharmaceutical factory was completed and put into production - after all, he is not in this profession.

The Medical Equipment Factory is a first-level unit, and the access control is strict.The iron-clad gate of the yard was tightly closed, and he rang the doorbell for a long time before a face appeared through the small window on the door——to Shi Yuren's surprise, it was a face that had been burned.

Then he remembered, this is a disabled soldier, and these people are basically guards in key departments now.

"Principal!" The guard saw that it was the dean of the hospital and the director of the factory, and quickly opened the door.

Although Shi Yanren had the impression that he had treated this person, he couldn't remember his name, so he just nodded politely: "Is Zhao Yanmei here?"

"Yes, yes," the doorman responded repeatedly, "You sit in the office first, and I will inform—"

"No, where is it? I'll find her myself."

"Director Zhao said," the guard thought for a moment, "No one else can come in when she is working. Let me notify you."

A room starting with 0 means it is in the basement.Probably the strain laboratory.Although Shi Yanren doesn't engage in biochemistry, she knows a little bit about the principle—probably she is doing something like cultivating bacteria, and doesn't want people to come in and bring in miscellaneous bacteria.

"How did you notify?" Shi Yanren became curious. Although there is a telephone here, there is no internal telephone.

"Use this." The guard limped and led him into the guard room.Inside, a shelf was built along the wall, divided into several rows, and each small nameplate was nailed to it. On the nameplate was a small bell and a pull cord.

The guard carefully wrote the date and the name of the visitor in the registration book in crooked fonts, and then pulled the rope under a certain nameplate a few times. After a while, the small bell on the nameplate also rang.

"Director Zhao knows. She will come out soon."

"? This system is not bad." Shi Yanren thought to himself that this is similar to the electric bell in the inpatient department of a hospital. Although it cannot communicate, it can at least convey simple information.Do you think this system can also be used in hospitals?I will ask Zhao Yanmei later.

Zhao Yanmei's office is separate, Shi Yanren sat for a long time before seeing her come back.

It turned out that Zhao Yanmei was inoculating kasugamycin in the strain laboratory.This kind of antibiotic is mainly used in agriculture to prevent crop diseases, and has little medical value-it is used to treat mild infections that are not serious.Shi Youren was a little dissatisfied—in his opinion, the co-organization with the Council of Agriculture would have such a result, and their needs should be fulfilled first.

Zhao Yanmei saw the leader's expression was not very lively, so she guessed his thoughts.

"This is also a practice!" She explained, "The local cultivation method of kasugamycin is relatively simple and does not require high environmental conditions. If this can be done, it will be easy to cultivate other strains later."

Shi Yanren hurriedly asked: "What kind of bacteria are you going to cultivate next? Can penicillin work?"

"Cultivating penicillin is not difficult, but purification is troublesome." Zhao Yanmei frowned, "The conditions should be better. For medical use, you can cultivate oxytetracycline first. This is relatively simple."

Oxytetracycline is also good. The effect of this thing is almost the same as that of tetracycline, which is quite a broad-spectrum antibiotic.

"Oxytetracycline is also good." Shi Yanren's face looked much better.

Zhao Yanmei's next sentence made Shi Yanren very unhappy: "It's also good for fattening pigs."

"Fattening pigs?"

"Yeah, that's what Lao Yang said." Lao Yang is naturally Yang Baogui.

"I'm afraid that there will not be enough medicines for people at that time. Now we are in short supply of antibiotics!" Shi Yanren expressed his heartache.

"No matter how urgent it is," Zhao Yanmei said, "The antibiotics produced have not been tested on animals, and the antibiotics produced under our conditions will have impurities, and there may be accidents if people eat them..."

"I can't take care of so much now." Shi Yanren said, "First solve the problem of existence and non-existence."

Zhao Yanmei came from a regular pharmaceutical factory, so she still doesn't quite get used to the simple, home-grown way of getting started.There was a moment of silence.

"It's not that important, is it?" Zhao Yanmei said, "The acid-alkali plant will be put into operation soon, and after it is put into operation, the coal chemical complex will also be put into operation. It will be fine once it is put into operation."

"I saw it in the newspaper." Shi Yanren was not interested in coal chemical companies. "There are many coal chemical products, probably synthetic ammonia? But they are all used in industry. Can antibiotics be produced?"

"Sulfa!" Zhao Yanmei said, "Ji Situi said that once this coal chemical complex is put into operation, the by-products will be sulfa raw materials."

Of course Shi Youren knew what sulfa meant.This chemical compound was first discovered in dyes and was the most effective anti-infective drug before penicillin antibiotics.In this time and space where bacteria have not developed drug resistance, this thing alone can save countless lives!

"Really?!" Shi Yanren was surprised and delighted, almost stood up, this is great news.

"Ji Situi is right. He is an expert, so he won't talk nonsense."

"Well, well, this matter needs to be followed up! Follow up!"

"Don't worry, the acid-base plant won't be ignited until the day after tomorrow, and the coal chemical plant will have to wait for some days. According to Ji Situi, there isn't even enough coal to be transported."

"Okay, let's not talk about this for now." When Shi Yanren remembered that his business was not to find antibiotics, he talked to Zhao Yanmei about the current health situation, and suggested that the pharmaceutical factory should be able to make some commonly used medicines in the near future.

"...antidiarrheals, saline, glucose solution, and bleach."

Zhao Yanmei said: "To be honest, the only things that can be delivered immediately are distilled water for injection, a dozen kinds of Chinese patent medicines, normal saline, and alcohol. Even making glucose is difficult..."

"Normal saline is still a problem," she continued. "The salt sodium chloride transported from the first salt farm village is not pure enough and has too many impurities. Second, there is not enough sulfuric acid. I dare not use normal saline for infusion. First, get some oral Bar."

"What do you need, I'll apply again to the Planning Commission!"

"I want too many things. I'm afraid the planning committee can't do anything - committee member Ma can't make something out of nothing." Zhao Yanmei smiled wryly, "Doctor Shi, you should know that modern pharmacy is actually chemistry."

"You mean—" Shi Yanren understood what she meant, "Not enough chemicals?"

"Not only is it not enough, it is simply in short supply. Let's talk about the glucose rehydration solution you want. The glucose process is very simple. The starch and acidification method are easy to make, but I don't have acid: neither hydrochloric acid nor sulfuric acid, so I have to use enzymes. Not to mention the time-consuming and labor-intensive chemical method, the pH value of the glucose produced cannot be corrected—there is no alkali.”

Shi Yanren nodded.

"Also, gauze, absorbent cotton. As usual, they need to be degreased first - there must be caustic soda. But now there is a shortage of caustic soda. There are not enough disinfectants available, and the products produced can only be said to be passable. Thanks to the large-scale trauma Not much." She stopped talking, "Except for bacteria cultivation and Chinese patent medicines, pharmaceutical factories really can't produce anything particularly effective."

"Don't worry, these things will be resolved in the next few days. Bopu's chemical plant will be put into operation soon. I told the planning committee to let the pharmaceutical factory take priority." Shi Yanren encouraged her.

"That's good. With three acids and two caustic sodas, many things can be made." She got up and took out a piece of paper from the drawer of her desk. "This is some things that need to be coordinated and urgently needed supplies."

Shi Yuren took it over and took a look, and there were many items listed on it: the machinery department was required to provide a knitting machine of special specifications for weaving gauze; a complete set of cutting equipment and workers who knew how to cut—this was used to make masks ; All kinds of oversized pots, clay pots, iron pots... The glass factory has the most orders: a large number of utensils, pipes and alcohol blowtorches.

"There are also small injection bottles." Zhao Yanmei said, "This is difficult to make, and the glass factory may not be interested. It needs to be directly issued by the Planning Commission for research and development."

"Are you going to make injections, oxytetracycline injections?"

"For the time being, we will make traditional Chinese medicine injections first. We are going to make some honeysuckle and banlangen injections, as well as cardiotonic drugs—it should be possible to refine atropine."

"This thing—" Shi Yanren still has some impressions of the death caused by traditional Chinese medicine injections back then, "Is it safe?"

"It's not safe enough. The ingredients of traditional Chinese medicine extracts are miscellaneous, and the pharmacological principles are not clear enough. However, traditional Chinese medicine injections such as honeysuckle, banlangen and Shuanghuanglian have been used for decades, and the mortality rate is acceptable, not very dangerous. As for atropine, it is a very dangerous thing. But atropine is an important rescue medicine and is very useful, so let’s make it first and try it out.”

"Okay." Shi Yanren knew that this was also a helpless move.

"I have another request." Zhao Yanmei continued, "It is best to keep all the empty bottles used in the hospital, such as injection bottles, infusion bottles, and medicine bottles, and hand them over to the pharmaceutical factory. We can reuse them."

These things are all kept. According to the regulations of the Planning Commission, any modern products cannot be discarded at will, and even those that are not needed for the time being must be stored first.

"These are kept. And all of them have been cleaned and disinfected. But they are all on the account of the Planning Commission. I will talk to the Planning Commission and approve them for you."

"One more request—" Zhao Yanmei probably felt that her request was a little too much, "Can you give us an X-ray machine?"

Shi Niaoren was startled. X-ray machine!This is special control equipment.Because of the issue of radioactive sources, the traversers managed to get only three of them after all their efforts, and at least they would have to rely on them for decades.What does the pharmaceutical company want this thing for?

(End of this chapter)