Genius of the Rules-Style System

In the past ten days, Zhao Yi has been sorting out his results, carefully preparing academic reports, and also thinking about the direction of continued research on the 'multidimensional space boundary'.

Research and thinking are very demanding on brain cells. Thinking seriously for a long time made him feel very tired. Occasionally he wanted to relax, so he simply went to the Institute of Biomedical Research.

The experimental work of the Biomedical Research Institute is indeed simple and clear to Zhao Yi. If he can get the results, he can directly use his abilities. If he can't get the results, he will probably be helpless.

"This is probably the difference in difficulty between science and technology?" Zhao Yi thought mockingly.

of course not.

Technology is also very difficult, but he has a system.

Zhao Yi's laboratory has not taken on any big projects for the time being. They still focus on a few small projects on AIDS research. The main person in charge is Zhang Wei.

Liu Chengjie and Yan Yi are working on small research projects that they have taken on personally. They are all trying to work on projects independently, which is also a process of growth.

Fan Lei still comes over every day to check in and see if there is anything he can do to help. What’s more important to him is that he is familiar with everyone in the institute, has a few words to get to know them, and learns about research needs by the way. He plans to work at the institute after graduation and engage in logistics-related work.

Logistics work is definitely not as good as direct research, and there are gaps in salary, benefits, and importance. However, Yan Xuelin promised a formal administrative position, which also has great potential.

Zhao Yi was sitting in the laboratory, looking at recent research materials.

Fan Lei opened the door and walked in. He said with surprise written all over his face, "Zhao Yi, here we come!"

"What's wrong? Are you so happy?"

"You don't know?" Fan Lei said, looking towards Liu Chengjie, and then he leaned over and said in a low voice, "I don't know whether to keep it a secret or not. I just met Director Yan downstairs and he said he would take me to fly to Wuhan tomorrow. City, let’s talk about a big deal!”

"Director Yan takes you to discuss big projects?" Zhao Yi was a little surprised.

"yes?"

Zhao Yi asked with some confusion, "How can you help?"

"Stop looking down on people."

Fan Lei patted his chest confidently and said, "I'm telling you, what I'm super good at is negotiating business. Don't say anything else. Just with my face, any opponent will give in. We just have good looks, there's nothing we can do about it. Others can’t learn from it!”

"……I see."

Zhao Yi stared at Fan Lei's face carefully and sighed, "Director Yan must have decided to take you with him because he thought you were thick-skinned enough."

"Hahaha……"

Fan Lei didn't care what Zhao Yi said. He followed the director around to discuss business. The most important thing was not to discuss business, but to gain the respect of the director.

Of course Zhao Yi doesn't care.

What he cares about is that without outstanding technical ability, he can only rely on his mouth to get a good job.

This is the reality.

…

Fan Lei excitedly talked about following Director Yan to discuss business, which made Zhao Yi feel a little confused.

Wucheng?

There is a pharmaceutical company that we cooperate with, it seems to be in Wucheng, right?

Talking about business?

Are you talking about the Medical Science Center...impossible!

The sponsorship and construction of the Medical Science Center has almost been negotiated. The medical enterprises will determine how much funding they will provide, and the funds will be in place. How to build the center and how to allocate the funds are matters for universities, colleges, and research institutes. There is no need to talk about it in particular.

So what kind of ‘big business’ can it be?

Three days later.

When Zhao Yizheng and Li Renzhe were nervously playing games together, Fan Lei opened the door and walked in, shouting, "I'm back!"

"..."

No one paid any attention to him.

Zhao Yi and Li Renzhe continued to be immersed in the game.

"Stop playing, Zhao Yi!" Fan Lei simply walked up behind Zhao Yi and said with a little tiredness, "Director Yan asked me to say hello to you and go to the research institute quickly."

"What's wrong?"

"It's a big deal. Go quickly. Come on, I'll help you fight!"

Zhao Yi stood up depressed, gave up his position to Fan Lei, and emphasized, "Don't die, I'm already at 7 bars and 0."

"OK!"

"I don't believe in your skills..."

Zhao Yi muttered dissatisfiedly, knowing that Fan Lei must be announcing some 'big business' when he came back. He didn't ask Fan Lei here because it might involve confidentiality issues, so he went directly to the research institute.

The small conference room of the institute.

Zhao Yi walked in and took a quick glance, and knew it must be related to 2CV-Bing Hydrogen Molecule, because several people sitting there were all involved in the project.

Dai Tianqing, Han Hui, Li Ming, Ai Lixin, Chen Zhigang, Zhang Wei, plus Yan Xuelin.

Liu Chengjie, Yan Yi and others in the laboratory also knew about the 2CV-Bing hydrogen molecule, but their level and ability were not enough, so they did not participate in subsequent research.

Yan Xuelin saw Zhao Yi walking in and quickly asked him to sit down. He said excitedly, "The pharmaceutical company we are cooperating with has encountered a problem in drug development!"

"ah?"

This matter had just been mentioned, and no one in the conference room knew it. They looked at each other and didn't understand why Director Yan was still happy when "drug development encountered problems."

Shouldn't you be depressed?

Anyway, they feel quite depressed because the drug development has encountered problems and the results have not been published for a long time. It is a major result in the medical field. After it is published, it will definitely attract world attention and maybe win a big prize.

Even if the winner is Zhao Yi, they can all take advantage of it as they participate in the project together!

In addition, they also publish papers with related side results, and papers with main results can also be signed.

For scientific researchers in any field, influential results, results and papers that have attracted great attention from the world are very, very important. Research results and papers are the results of their work, and getting more attention means that they the success of scientific research work.

Everyone looked at Yan Xuelin with doubts.

Yan Xuelin smiled and said, "This time I went to Wucheng just for drug development. Since the results are ours, they invited our institute to do drug development simultaneously."

"You mean, there's another large amount of sponsorship?" Dai Tianqing was the first to react.

Ailixin asked hesitantly, "But we are not specialized in drug development. We may not be able to solve the problems that their pharmaceutical companies encounter."

Yan Xuelin waved his hand and said, "It doesn't matter. Because of confidentiality issues, they can't share the information. They have no other choice but to find us for simultaneous development."

"Synchronize……"

Dai Tianqing said hesitantly, "Does this mean that information is not shared and each develops independently?"

Yan Xuelin nodded affirmatively, "Yes! We are doing development at the same time, and they will pay for the funds. If there are results, we will also have a part of the patent fees. This is what I am going to talk about this time, with an initial sponsorship of 10 million. If in the end What we can produce can occupy 30% of the drug patents."

"They sponsored it, thirty-seven points... quite good..." Dai Tianqing commented.

Ai Lixin said, "But it may not produce any results. The scientific research teams of pharmaceutical companies will definitely encounter big problems."

Yan Xuelin smiled and said, "Lao Ai, don't lose confidence. This hasn't started yet. The most important thing is that even if we can't get results, we haven't lost anything."

"That's right." Everyone else nodded thoughtfully.

This matter is very clear.

Pharmaceutical companies encountered problems in drug development and found that they could not be solved in a short time, so they simply asked the research institute to help develop them together. Compared with the research and discovery of 2CV-Binghydrogen molecules, no amount of scientific research funding is nothing.

They cannot find other institutions, because confidentiality is not only for the research institute, but also for people in the pharmaceutical company who know the information. They can either do their own research, or they can ask the research institute to help them research together.

Yan Xuelin went to Wucheng to discuss this matter. The final result of the discussion was that pharmaceutical companies sponsored research institutes to conduct drug development simultaneously, and the results were calculated based on patents. They accounted for 70% of the patent ownership ratio.

Any scientific research institution hopes to attract external corporate sponsorship funds. The Institute of Biomedical Sciences is a national scientific research unit, and most of the R\u0026D funds come from the state, because most of them are engaged in research on medical mechanisms. Real external corporate sponsorship There is not much funding for scientific research.

The scale of the Biomedical Research Institute is not small, but with an initial funding of 10 million, it is definitely a super large project. More importantly, the institute almost suffers any losses, and the funding is provided by pharmaceutical companies. Producing results can also allow participating researchers to gain some experience in drug development.

It would be even better if results are produced. The 30% patent ownership is actually quite a lot, and that is the patent for the 2CV-Binghydrogen molecule drug.

The institute is very familiar with the effects of 2CV-Binghydrogen molecules. The drugs developed with 2CV-Binghydrogen molecules as the main body will definitely have good effects on AIDS. They may be popular domestically and internationally. 30% of the drug patents can Bring a steady stream of large profits.

In addition, the development of AIDS drugs is also of great significance. So far, there are no self-marketed AIDS drugs in China, and all drugs used for treatment are imported. The research institute discovered the effect of 2CV-bihydrin molecules, and added a 'developed The title of "Relevant Drugs" will definitely be doubled in honor.

Financial interests and honor, the two combined are enough to attract anyone.

…

Yan Xuelin broke the big news about simultaneous drug development, and the internal small meeting had just begun. He went to the drug research and development base of Wucheng Pharmaceutical Company and learned about the difficulties encountered in drug research and development.

To put it simply, there is currently no method to artificially synthesize 2CV-Binghydrogen molecules. The cost of producing 2CV-Binghydrogen molecules relying on the immune process in a laboratory environment is too high, and the efficiency is too low.

The latter becomes clear as soon as you say it.

In the previous research on 2CV-Bing Hydrogen molecules, the laboratory's production methods were to simulate the immune environment, produce antibodies against the invasion of bacilli, and incidentally create 2CV-Bing Hydrogen molecules.

If you want to extract 2CV-bing hydrogen molecules, you need to constantly interrupt the experiment and add many types of chemical materials. The process is very complicated. To extract a small tube of solution containing a small amount of 2CV-bing hydrogen molecules, the laboratory cost can easily reach Over ten thousand.

This small tube of solution is used for actual treatment. It is estimated that it is only enough to be injected into the human body two or three times. It is all used up before the effect is even seen. However, it is generally estimated that the 2CV-Binghydrogen molecule drug will need to be injected continuously. It takes more than half a month, even one month or two months, until all HIV in the blood is 'controlled' to achieve very good results.

To put it simply, if injected once a day, the drug costs more than 3,000 RMB, and the average use lasts for one month, which is 100,000 RMB.

This is the cost of the drug in the lab.

When selling in the market, R\u0026D costs, profits, etc. must be taken into consideration. It is easy to increase the price several times or dozens of times, but it is definitely not within the reach of ordinary people.

Pharmaceutical companies have a bigger concern.

After the drug is officially launched, the ingredients will definitely be disclosed, and counterfeit drugs will soon appear. However, many international pharmaceutical companies have stronger R\u0026D capabilities. They may be able to mass-produce 2CV-bihydrin molecules, and the drug will be fully launched. It's like making wedding clothes for others.

After Yan Xuelin finished explaining the problems he encountered, the first person to speak was Li Ming. Li Ming had done biochemistry projects and had certain relevant experience. He directly 'drawn the line' on research and development, "Artificial synthesis cannot It’s possible, at least not possible in the short term, and we still have to look for biological means in our research and development.”

Yan Xuelin nodded and said, "There is no need to consider the issue of artificial synthesis. We still have to find methods in the fields we are good at."

The method of artificial synthesis is simple and direct, but it is difficult because of its simplicity. Not to mention that it takes a long time. The research institute lacks relevant experience. Even if it tries hard to research the method, it does not even have a lot of required equipment.

Doing research from a biological experimental perspective is different.

The institute specializes in this direction.

Several researchers thought for a while and quickly came up with several directions——

"We need to find a way to replace the human immune environment, as long as we can produce 2CV-Bing hydrogen molecules normally." Han Hui said that the way is to reduce costs. It is very expensive to simulate the human immune environment. If you replace unnecessary ones, you can Reduce the cost of simulation environment to a great extent.

Dai Tianqing’s opinion is, “We can study the immune response of other vertebrates on bacilli, and we may be able to find 2CV-binhydrogen molecules, or similar small protein substances with similar anti-AIDS effects.”

His advice was somewhat 'hit and miss'.

If you are lucky enough to discover that the immune system of mice and the immune process against bacilli can also produce small protein substances that can fight HIV, there will be many other research directions or direct mass production methods.

Li Ming made a different proposal, "We can study human bacilli antibodies. Bacteria antibodies are macromolecular proteins that are produced together with 2CV-Bing hydrogen molecules. We may make other discoveries."

This suggestion is a bit vague and does not seem to have much to do with drug development, but it may lead to new discoveries. Research on drug development from a biological perspective is not as "simple and crude" as artificial synthesis. More Discovery leads to better ways.

After several researchers had expressed their opinions, everyone in the small conference room looked at Zhao Yi.

In fact, Zhao Yi rarely expresses his opinions in similar meetings because he has very little knowledge and experience, and it is difficult for him to have good suggestions.

Zhao Yi thought for a moment and did not express his opinion. Instead, he said directly, "I support Professor Li Ming's opinion that research should be conducted on bacilli."

"Why?" Yan Xuelin asked with interest.

Zhao Yi thought for a while and said, "Just intuitive."

"intuition?"

Dai Tianqing couldn't help but said, "Zhao Yi, we can't rely on intuition when doing research, we must speak with science."

"oh."

Zhao Yi nodded and accepted the education, but still insisted, "But I still think that we should focus on studying bacterium antibodies, and other things can assist."

Yan Xuelin thought for a moment and nodded, "Everyone's opinions are reasonable. Drug development is not a single study. Breakthroughs in each direction may reduce manufacturing costs."

"Let's do this. We will do research separately in the early stage. There will be three groups, one group with one direction, all based on their own ideas, and finally merged together."

Li Ming took the lead in nodding and said, "Zhao Yi and I have the same opinion, let's work together."

Zhang Wei raised her hand and said, "I am in this group, too. Zhao Yi is very busy and has to prepare academic reports. We have more experience working together."

"No, you guys, I think..."

Ai Lixin remembers that he didn't even finish his sentence. He wanted to be in a group with Zhao Yi, but Li Ming said it first, and Zhang Wei quickly raised her hands to express her gratitude. When he was feeling depressed, Han Hui said, "You will be in a group with me." Bar."

He could only nod helplessly, thinking about the direction of replacing the human body environment. At least there would be no progress. It was better than trying his luck with Dai Tianqing.

Dai Tianqing and Chen Zhigang looked at each other, nodded and said, "Then we will be a team."

…

After the internal small meeting, everyone walked out one after another.

When Dai Tianqing went out, he smiled and said, "Zhao Yi, let me tell you, we have too little experience in drug development projects and cannot keep up with the R\u0026D capabilities of pharmaceutical companies. If they can't do it in a short time, it will be difficult for us. "

"So doing this is a matter of luck. We are divided into three groups. I think if there is any result, it must be our group."

Chen Zhigang thought it made sense after listening to it, and immediately thought that it would be good to be in the same group as Passive and Dai Tianqing.

Zhao Yi smiled and gave Dai Tianqing a thumbs up, "Well, I wish you success, come on!"

"Come on, you guys too!"

The two looked at each other and smiled at the same time.