godfather of surgery

Chapter 1002 Checklist Puzzle
Checklists were laid out one by one on the huge conference table. In order to prevent the wind from blowing the checklists away, Yang Ping asked the students to close the doors and windows of the entire conference room.

Yang Ping constantly adjusted the positions of the checklists, just like a child playing a puzzle. Through repeated adjustments, these checklists were not only arranged by time, but also classified by type. Then, different checks were sorted out according to their internal logical relationships.

"Don't touch them. Is there any more information?" Yang Ping was now completely immersed in analyzing these checklist puzzles.

The doctor who had just gone to get the checkup sheets said, "They are all here. He puts them in a box every time he sees a patient, and he takes a photo of each one for record."

He is a serious and meticulous person, and perhaps this seriousness can save his life. If there is no better way, according to current literature statistics, Fu Xiaotao will hardly live more than two years.

Song Zimo was a little nervous: "Did you find anything?"

"These are the objective and complete pictures of the entire disease that we can obtain. Let's see, if we regard each outbreak as a local part, then from the local analysis, it is true that its pathogenesis is based on interleukin 6. But now if you combine all the single outbreaks and look at the entire disease process, is the interleukin 6 model still correct?" Yang Ping already had some new ideas in his mind.

When you carefully analyze many things comprehensively and in depth, the results will be very different, because perhaps no one has ever really analyzed them so seriously before you.

Song Zimo, Xu Zhiliang, and every other doctor around came closer to take a look, but they all kept a small distance, for fear that their breath would accidentally blow away a check list.

"I am grateful to every doctor for doing their best to complete the examination and collect information. Vascular endothelial growth factor was found in many examinations. Although there were a few times when it was not examined, the trend can still be roughly seen." Yang Ping walked around the conference table.

Song Zimo listened to Yang Ping's mumbling and read the vascular endothelial growth factor test sheets one by one in chronological order. He looked at its development trend from the entire disease process and then at each attack process. Indeed, it was not interleukin-6 but vascular endothelial growth factor that ran through the entire process.

"Are you saying that vascular endothelial growth factor is the possible basis for the entire disease? Or the interleukin 6 model is wrong and should be revised to the vascular endothelial growth factor model?" Song Zimo found Yang Ping's statement unbelievable.

The interleukin-6 model is the pathogenesis of Castleman's disease recognized by the academic community. Now, it is too much of a joke to overturn a world-recognized model based on just one case and a pile of test lists. However, this is Professor Yang, and Song Zimo has to believe it.

In fact, Yang Ping has spent a lot of time studying this case in the system space, and he is definitely not just casually pointing out such a question now.

Yang Ping walked around the desk, then stopped, resting his hands on the conference table, staring at the test results for five minutes before speaking: "We can try to block the pathway that triggers VEGF production and activates T cells to inhibit the occurrence of the disease! If the patient is willing, we can use the advantages of the laboratory to re-analyze his disease."

"Shall I go talk to him?"

"No, I'll go talk to him myself."

Yang Ping felt that he seemed to have grasped the true pathogenesis of Castleman's disease. After overturning the original theory, he felt that his theory could better explain Fu Xiaotao's condition. If judged according to the diagnostic monism, his theory could explain more clinical symptoms than interleukin-6.

After he had a clear idea in his mind, Yang Ping asked his students to take photos of all the checklists as they were arranged by him, and then take photos of each checklist separately. He hoped to draw a trend chart of the changes in these checklist indicators. This work was rather tedious, but these doctoral and master's students were eager to do it.

Without wasting any time, Yang Ping and Song Zimo came to the Department of Oncology. Director Jiang went out to participate in a case discussion. Yang Ping and Song Zimo went to find Fu Xiaotao under the guidance of the attending physician.

Fu Xiaotao was not in a very good mental state, because he had just survived with high-dose chemotherapy not long ago. When he got sick this time, he was hospitalized for the first time and used high-dose hormones to control the disease, and then used cetuximab for treatment. In the past, after stopping hormones, the disease did not relapse so quickly. Perhaps this time it was not a relapse at all, but the disease was not under control. High-dose hormones only temporarily controlled the symptoms. Once the hormones were stopped, the disease continued to develop until this fatal outbreak.

"Professor Yang!" Fu Xiaotao climbed up from the bed with difficulty.

Yang Ping and Song Zimo helped him to a semi-sitting position against the pillow. Fu Xiaotao's parents had been waiting beside him. They looked obviously unhappy because his condition had not improved after Yang Ping's last consultation and it had become so serious.

However, Fu Xiaotao still believed in Yang Ping. He had looked up a lot of information and knew the complexity of his illness.

Yang Ping didn't care about that and said to Fu Xiaotao, "We have thought more deeply about your disease and found that the existing treatments are simply incapable of curing your disease. We now want to use a new method for you, but the new method is for scientific research and has not been used by anyone else. It has certain risks, so we must obtain your consent."

"How can that be possible!" Fu Xiaotao's mother rejected it outright.

Fu Xiaotao's father said gently, "Let the professor finish what he is saying. The new method is definitely experimental. Don't be disgusted by hearing about the experiment. Let's go out first and let the child talk to the professor."

Fu Xiaotao's father took his wife out to avoid interfering with the doctor's communication with his son. Fu Xiaotao's mother followed him out unhappily.

"Professor Yang, don't worry about it. They don't understand. I am willing to sign and participate in the scientific research method you just mentioned." Fu Xiaotao completely agreed.

Yang Ping told him: "After all, this is scientific research, and there are certain risks. Can you accept it? And it is likely to fail again."

Fu Xiaotao smiled bitterly and said, "I know my disease very well. There is no good way to cure it. Since there is no way, why don't I try a new method that may be effective now?"

"And if we use the new method, we will draw blood from you and do a lot of tests, because we need to figure out the changes in some of your current biochemical indicators in your body." Song Zimo added an explanation.

Fu Xiaotao was very determined: "It's okay, you guys make the arrangements."

As a graduate student, Fu Xiaotao had checked Yang Ping's thesis. He was shocked to find that he was an academic giant. Such a giant would not have the time to talk nonsense with an ordinary patient like you. He must have known something about it, so he came to you personally to propose this experimental method. The desire to survive made Fu Xiaotao hold on to this life-saving rope tightly. Under normal circumstances, he might not be able to invite such a giant even if he wanted to. Now that he has come to him, if he refuses, he will miss the precious opportunity.

Moreover, Fu Xiaotao always believes that doctors and patients are comrades-in-arms and their common enemy is disease.

"Do you really agree? Do you want to discuss it with your parents?" Song Zimo reminded.

Fu Xiaotao shook his head: "No, I'm an adult and can decide for myself. If I discuss this with them, it will definitely not work. My dad is fine, but my mom will definitely not agree."

"Okay, if you agree, I will talk to the doctor here and transfer you to our department for treatment. All expenses for the scientific research treatment will be free, and you can also receive a certain amount of allowance." Yang Ping settled the matter on the spot.

"Thank you! It's settled. You can come to me for signature at any time." Fu Xiaotao was very determined.